Which lipoprotein is formed in the blood from VLDL and carries cholesterol throughout the body?

• A. High-Density Lipoprotein (HDL)
• B. Chylomicrons
• C. Low-Density Lipoprotein (LDL)
• D. Very Low Density Lipoprotein (VLDL)

Answer: (C)

Lipoprotein metabolism shifts triglyceride-rich VLDL into cholesterol-rich particles that travel in the blood to tissues. When triglycerides are removed by lipoprotein lipase, VLDL is remodeled first into IDL and then into LDL. The resulting LDL particle is loaded with cholesterol and serves to deliver cholesterol to cells throughout the body via LDL receptors. In contrast, chylomicrons carry dietary fats from the intestine, and HDL provides a route for excess cholesterol to be returned to the liver.